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What’s the difference between cis and trans recombination?

I’ve got a genetics problem asking about what the genotype of certain flies in a test cross would be if the alleles were in the cis arrangement; and another question further along asking about trans arrangement.

The problem is I’m not really sure what the difference is (between cis and trans arrangement)!

Please help :)
"Cis" means one chromosome has both dominant alleles and its homologous has both recessive alleles.
==> AB/ab

"Trans" means one chromosome has one dominant allele and on recessive allele, and vice versa.
==> Ab/aB

These linkage phases will determine the proportion of parental and recombinant types if a crossover occurs between the two genes.

This entry was posted on Monday, August 31st, 2009 at 10:20 pm and is filed under trans. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

2 Responses to “What’s the difference between cis and trans recombination?”

  1. If mutations x and y are on the same DNA strand we say that they are in "cis" and if they are on different DNA strands we say that they are in "trans." In the case of flies it would be on the same chromosome (cis) or a different chromosome (trans).

    http://www.escience.ws/b572/L13/L13.htm - describes the cis-trans test.
    References :

  2. "Cis" means one chromosome has both dominant alleles and its homologous has both recessive alleles.
    ==> AB/ab

    "Trans" means one chromosome has one dominant allele and on recessive allele, and vice versa.
    ==> Ab/aB

    These linkage phases will determine the proportion of parental and recombinant types if a crossover occurs between the two genes.
    References :

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